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2009 Design of Medical Devices Conference Abstracts

A Wireless, Passive pH Sensor Based on Magnetic Higher-Order Harmonic Fields OPEN ACCESS

[+] Author and Article Information
B. Horton, E. Tan, B. Pereles, K. Ong

 Michigan Technological University, Houghton, USA

J. Med. Devices 3(2), 027548 (Jul 24, 2009) (1 page) doi:10.1115/1.3147252 History: Published July 24, 2009

Abstract

A wireless, passive sensor was fabricated for remote monitoring of chemical analytes in the human body. The sensor was made of a magnetically soft film (sensing element) and a permanent magnetic film (biasing element) sandwiching a reversibly swelling hydrogel. When subjected to a low frequency magnetic AC field, the sensing element generated higher-order harmonic magnetic fields that were detected with a remotely located detection coil. In the presence of a DC magnetic field (biasing field), such as that generated from the biasing element, the pattern of the higher-order harmonic magnetic fields varied, and the magnitude of change (referred to as the harmonic field shift) was proportional to the strength of the biasing field. The hydrogel, which acted as a transducer that converted variations in the chemical concentration into changes in dimensions, physically varied the separation distance between the sensing and the biasing elements. This causes a change in the magnitude of biasing field experienced by the sensing element, thus changing its higher-order harmonic field shift allowing remote measurement of chemical concentrations. The novelty of this sensor was its wireless and passive nature, which allows it to be used inside a human body for long term chemical monitoring. A scaled-up prototype was fabricated and tested to demonstrate the pH monitoring capability of the sensor. The main structure of the prototype sensor was a polycarbonate substrate containing a larger rectangular well of 36mm×8mm×4mm on top of a smaller well of 30mm×5mm×2mm (see Fig. 1). The smaller well was filled with hydrogel made of (poly)vinyl alcohol and (poly)acrylic acid. A commercial magnetoelastic thick film, Metglas 2826MB from Metglas Inc., was attached to the step at the bottom of the larger well and allowed to rest on the hydrogel. The DC magnetic field was provided by an Arnokrome III film (Arnold Magnetic Technologies) of 30mm×6mm attached at the bottom of the sensor structure. The sensor was placed on the detection coil, and its response was measured with a spectrum analyzer while exposed to test solutions of varying pH. The sensor's harmonic field shift, when cycled between pH 7 and pH 3, was measured and plotted in Fig. 2. As shown in the figure, the hydrogel swelled when the sensor was exposed to pH 3, decreasing the harmonic field shift. The response and recovery times of the hydrogel were below 2 minutes. This experiment proves the feasibility of the technology for real-time, remote monitoring of pH. Further work includes improving the response time and sensitivity of the hydrogel, as well as miniaturization of the sensor.

Copyright © 2009 by American Society of Mechanical Engineers
Topics: Sensors
This article is only available in the PDF format.

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