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2008 Design of Medical Devices Conference Abstracts

Imaging Depth-Resolved Tissue Birefringence With a Single Detector OPEN ACCESS

[+] Author and Article Information
Muhammad K. Al-Kaisi, Taner Akkin

University of Minnesota

J. Med. Devices 2(2), 027559 (Jun 25, 2008) (1 page) doi:10.1115/1.2936214 History: Published June 25, 2008

Abstract

We report a novel frequency multiplexed optical coherence tomography (FM-OCT) system that is capable of measuring depth-resolved tissue birefringence from a single record of a single detector. The FM-OCT system utilizes polarization-maintaining-fiber based components. The orthogonal channels of the polarization-maintaining-fiber and the cross-terms are frequency multiplexed. After recording the interference signal, a set of digital band-pass filters extract the polarization information. A rapid scanning optical delay line in the reference arm compensates for dispersion and allows a real-time display of tissue birefringence. The axial resolution provided by a superluminescent diode working at 855nm with 28nm bandwidth is 12μm. The accuracy and sensitivity measurements suggest that the FM-OCT system is suitable for depth-resolved birefringence characterization of biological tissue.

Copyright © 2008 by American Society of Mechanical Engineers
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