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Research Papers

Two-Dimensional Optimization of a Stent for an Aneurysm

[+] Author and Article Information
K. Srinivas1

School of Aerospace, Mechanical and Mechatronic Engineering, University of Sydney, New South Wales 2006, Australia; Institute of Fluid Science, Tohoku University, 980-8577 Japank.srinivas@usyd.edu.au

S. Townsend, C. J. Lee

School of Aerospace, Mechanical and Mechatronic Engineering, University of Sydney, New South Wales 2006, Australia

T. Nakayama, M. Ohta, S. Obayashi

Institute of Fluid Science, Tohoku University, 980-8577 Japan

T. Yamaguchi

Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University, 980-8577 Japan

1

Corresponding author.

J. Med. Devices 4(2), 021003 (Aug 04, 2010) (7 pages) doi:10.1115/1.4001861 History: Received April 02, 2009; Revised April 23, 2010; Published August 04, 2010; Online August 04, 2010

This work attempts to optimize stents that are implanted at the neck of coronary or cerebral aneurysms to effect a flow diversion. A two-dimensional version of the stent, which is a series of struts and gaps placed at the neck, is considered as the first step. Optimization is carried out based on the principles of exploration of design space using reductions in velocity and vorticity in the aneurysm dome as the objective functions. Latin hypercube sampling first develops 30–60 samples of a strut-gap arrangement. Flow past an aneurysm with each of these samples is computed using the commercial software FLUENT and the objective functions evaluated. This is followed by a Kriging procedure that identifies the nondominated solutions to the system, which are the optimized candidates. Three different cases of stents with rectangular or circular struts are considered. It is found that placing struts in the proximal region of the neck gives the best flow diversion.

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Copyright © 2010 by American Society of Mechanical Engineers
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Figures

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Figure 1

Geometry of the aneurysm considered: (a) the vessel with the aneurysm and (b) enlarged view of the aneurysm dome with a stent

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Figure 2

Boundary conditions for flow computation

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Figure 3

An enlarged view of grid around struts

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Figure 4

Velocity vectors and vorticity contours for no-stent case

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Figure 5

Velocity vectors, vorticity contours, and strut arrangements for case 1: (a) best stent, (b) worst stent, and (c) compromise stent

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Figure 6

Nondominated front, case1

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Figure 7

Velocity vectors, vorticity contours, and strut arrangements for case 2: (a) best stent, (b) worst stent, and (c) compromise stent

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Figure 8

Nondominated solution for case 2

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Figure 9

Velocity vectors, vorticity contours, and strut arrangements for case 3: (a) best stent, (b) worst stent, and (c) compromise stent (with constraints applied)

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Figure 10

Nondominated solution, case 3

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Figure 11

Nondominated solution, case 3 with constraints

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