Technical Briefs

Device Optimization Using Pulse Wave Analysis Techniques

[+] Author and Article Information
Ashish Singal

Department of Biomedical Engineering,
University of Minnesota;
Department of Surgery,
University of Minnesota;
Department of Medical Devices Center,
University of Minnesota

Mitsuhiro Oura

Department of Medical Devices Center,
University of Minnesota

Mohamed Almekkawy

Department of Electrical and Computer Engineering,
University of Minnesota

Peter Eckman

Department of Cardiovascular Division,
University of Minnesota

Manuscript received March 15, 2013; final manuscript received May 1, 2013; published online May 30, 2013. Editor: Gerald E. Miller.

J. Med. Devices 7(2), 020903 (May 30, 2013) (2 pages) Paper No: MED-13-1029; doi: 10.1115/1.4024431 History: Received March 15, 2013; Revised May 01, 2013

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Fig. 4

Mean value following digital subtraction of PS's. Paired t-test p < 0.0025

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Fig. 3

Percent difference with respect to ON state of IABP. A: Mean Value; B: RMS value. Paired t-test p < 0.005.

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Fig. 2

Left column (blue) shows the 18 second blood pressure waveform and right column (red) shows the respective power spectrum within dominant frequency range

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Fig. 1

Block diagram illustrating the acquisition of physiological signal of interest and utilizing digital signal processing techniques to optimize ventricular assist device parameters to achieve better device performance and better patient outcomes. As illustrated in the block diagram, there are 3 potential paths. In the first path, physiological signals are acquired from the patient as applanation tonometry data, digital signal processing and analysis is performed, and the data is fed back to the implanted pump to optimize performance. In the second path, physiological signals are acquired from the implanted pump, analyzed and fed back to the pump to optimize its performance. In the third path, the current implanted pump performance is compared to a predefined matched state (shown in green), optimized, and fed back to the pump in a way that minimizes the error between the two states.



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