Technical Briefs

Using Modeling and Simulation in the Design of Closed-Loop Insulin Delivery System

[+] Author and Article Information
Arvind Ananthan

MathWorks, Inc.

Manuscript received March 15, 2013; final manuscript received April 25, 2013; published online June 12, 2013. Editor: Arthur G. Erdman.

J. Med. Devices 7(2), 020923 (Jun 12, 2013) (2 pages) Paper No: MED-13-1080; doi: 10.1115/1.4024340 History: Received March 15, 2013; Revised April 25, 2013

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Kovatchev, B. P., Breton, M., Man, C. D., and Cobelli, C., 2009, “In Silico Preclinical Trials: A Proof of Concept in Closed-Loop Control of Type 1 Diabetes,” J. Diabetes Sci. Technol., 3(1), pp. 44–55. [PubMed]
Continuous Glucose Monitoring and Closed-Loop Systems, Havorka, R., s.l.: Diabetic Med.,23, pp. 1–12.
. JohannesPlank, JanBlaha, JeremyCordingley, Malgorzata E.Wilinska. Alexandria, Virginia: American Diabetes Association, 2005. Diabetes Care. Vol. 29.
, ChiaraZecchin, AndreaFacchinetti, GiovanniSparacino, and ClaudioCobelli. Diabetes Technology & Therapeutics.
Kuhn, Dolores R.Wallace and D.Richard. Lessons from 342 Medical Device Failures. Gaithersburg, MD: Information Technology Laboratory, National Institute of Standards and Technology.
When code can kill or cure. The Economist, Jun 2nd2012.
Applying STPA to the Artificial Pancreas for People with Type 1 Diabetes, Lane Desborough, Medtronic http://tinyurl.com/usingSTPA
Case Studies of Modeling and Simulation Used in the Design of Devices Such as Emergency Ventilators (Weinmann Medical Technology) and Infusion Pumps (Medrad).





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