Technical Briefs

All-Optical Photoacoustic Detection of Absorbers in Tissue Phantoms

[+] Author and Article Information
Michelle Sabick

Department of Mechanical and Biomedical Engineering,
Boise State University

Kasper VanWijk

Department of Geosciences,
Boise State University

Manuscript received March 15, 2013; final manuscript received April 29, 2013; published online July 3, 2013. Assoc. Editor: Arthur G. Erdman.

J. Med. Devices 7(3), 030901 (Jul 03, 2013) (2 pages) Paper No: MED-13-1032; doi: 10.1115/1.4024483 History: Received March 15, 2013; Revised April 29, 2013

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Guo, Z., Hu, S., and Wang, L. H. V., 2010, “Calibration-Free Absolute Quantification of Optical Absorption Coefficients Using Acoustic Spectra in 3D Photoacoustic Microscopy of Biological Tissue,” Opt. Lett., 35(12), pp. 2067–2069.
Allen, T. J., Hall, A., Dhillon, A. P., Owen, J. S., and Beard, P. C., 2011, “Spectroscopic Photoacoustic Imaging of Lipid-Rich Plaques in the Human Aorta in the 740 to 1400 nm Wavelength Range,” J. Biomed. Opt., 17(6), p. 061209. [CrossRef]
Balogun, O., and Murray, T. W., 2011, “Frequency Domain Photoacoustics Using Intensity-Modulated Laser Sources,” Nondestructive Testing and Evaluation, 26(3−4), pp. 335–351. [CrossRef]
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Grahic Jump Location
Fig. 3

B-scan of phantom with tube and dye 34 mm below the source-surface. The wave generated (a) 34 mm below the surface and (b) at the phantom surface are indicated by arrows. The time of arrival of the waves generated at both the surface and tube increases hyperbolically as the detection beam scans away from the source and tube.

Grahic Jump Location
Fig. 2

A-scan measurements from middle of scan, with PA waves generated by infrared dye in tubes (a) 34 mm, (b) 20 mm, and (c) 13 mm below the surface and (d) ultrasound wave generated at the surface of the phantom (source-side).

Grahic Jump Location
Fig. 1

Experimental set-up, with thin-walled tube and dye shown in tissue phantom. The pulsed source beam is incident on the phantom surface. Photoacoustic waves are generated at the surface and in the tube, which are detected with an interferometer on the opposite surface.



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