Technical Briefs

Predicting Regional Brain Cooling Following Intracranial Thrombectomy With Localized Therapeutic Hypothermia

[+] Author and Article Information
Ryan A. Sikorski

Department of Mechanical Engineering,
Rowan University,
201 Mullica Hill Road,
Glassboro, NJ 08028
e-mail: sikors95@students.rowan.edu

Denise R. Merrill

FocalCool, LLC,
107 Gilbreth Parkway,
Mullica Hill, NJ 08062

Thomas L. Merrill

Department of Mechanical Engineering,
Rowan University,
201 Mullica Hill Road,
Glassboro, NJ 08028

Manuscript received March 15, 2013; final manuscript received April 26, 2013; published online July 3, 2013. Assoc. Editor: Arthur G. Erdman.

J. Med. Devices 7(3), 030927 (Jul 03, 2013) (2 pages) Paper No: MED-13-1085; doi: 10.1115/1.4024514 History: Received March 15, 2013; Revised April 26, 2013

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Grahic Jump Location
Fig. 1

In-vitro experimental canine vasculature, the inner carotid artery bifurcates to an exit point and the middle cerebral artery. The middle cerebral branches then are collected to a central tube for temperature and flow measurements.

Grahic Jump Location
Fig. 2

Experimental data compared to model predictions with varying flow rates. The temperature difference reaches a peak of 0.70 C at 130 ml/min flow rate. All computational values are within 2.1% of the experimental data.




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