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Technical Briefs

Artery Remodeling in Hypotension Using a Topology Optimization Method

[+] Author and Article Information
Linxia Gu

Department of Mechanical and Materials Engineering,
University of Nebraska–Lincoln

Manuscript received March 15, 2013; final manuscript received April 26, 2013; published online July 3, 2013. Assoc. Editor: Arthur G. Erdman.

J. Med. Devices 7(3), 030929 (Jul 03, 2013) (2 pages) Paper No: MED-13-1087; doi: 10.1115/1.4024518 History: Received March 15, 2013; Revised April 26, 2013

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References

Ambrosi, D., and Guana, F., 2007, “Stress-Modulated Growth,” Math Mech Solids, 12(3), pp. 319–342. [CrossRef]
Rachev, A., and Gleason, R. L., Jr., 2011, “Theoretical Study on the Effects of Pressure-Induced Remodeling on Geometry and Mechanical Non-Homogeneity of Conduit Arteries,” Biomech Model Mechanobiol, 10(1), pp. 79–93. [CrossRef] [PubMed]
Taber, L. A., 1995, “Biomechanics of Growth, Remodeling, and Morphogenesis,” Appl. Mech. Rev., 48(8), pp. 487–545. [CrossRef]
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Gleason, R. L., Taber, L. A., and Humphrey, J. D., 2004, “A 2-D Model of Flow-Induced Alterations in the Geometry, Structure, and Properties of Carotid Arteries,” J Biomech Eng, 126(3), pp. 371–381. [CrossRef] [PubMed]
Rachev, A., Stergiopulos, N., and Meister, J. J., 1998, “A Model for Geometric and Mechanical Adaptation of Arteries to Sustained Hypertension,” J Biomech Eng, 120(1), pp. 9–17. [CrossRef] [PubMed]
Taber, L. A., 1998, “A Model for Aortic Growth Based on Fluid Shear and Fiber Stresses,” J Biomech Eng, 120(3), pp. 348–354. [CrossRef] [PubMed]
Taber, L. A., and Eggers, D. W., 1996, “Theoretical Study of Stress-Modulated Growth in the Aorta,” J Theor Biol, 180(4), pp. 343–357. [CrossRef] [PubMed]
Taber, L. A., and Humphrey, J. D., 2001, “Stress-Modulated Growth, Residual Stress, and Vascular Heterogeneity,” J Biomech Eng, 123(6), pp. 528–535. [CrossRef] [PubMed]
Rodriguez, J., Goicolea, J. M., and Gabaldon, F., 2007, “A Volumetric Model for Growth of Arterial Walls With Arbitrary Geometry and Loads,” J Biomech, 40(5), pp. 961–971. [CrossRef] [PubMed]

Figures

Grahic Jump Location
Fig. 1

The element pseudo-density distribution (left) and stress intensity distribution (right) on straight artery after remodeling

Grahic Jump Location
Fig. 2

The element pseudo-density distribution on the middle segment of the tortuous artery during remodeling process

Grahic Jump Location
Fig. 3

The element pseudo-density distribution (left) and stress intensity distribution (right) on tortuous artery after remodeling

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