Frontiers Abstracts

Statistical Shape Modeling and Population Analysis of the Aortic Root of TAVI Patients

[+] Author and Article Information
Bart Bosmans

K.U. Leuven,
Leuven 3000, Belgium
Universiteit Antwerpen,
Antwerp 2000, Belgium
Materialise N.V.,
Leuven 3000, Belgium;
e-mail: bart.bosmans@mech.kuleuven.be

Toon Huysmans, Johan Bosmans

Universiteit Antwerpen,
Antwerp 2000, Belgium

Peter Verschueren

Materialise N.V.,
Leuven 3000, Belgium

Jos Vander Sloten

K.U. Leuven,
Leuven 3000, Belgium

Manuscript received October 1, 2013; final manuscript received October 29, 2013; published online December 5, 2013. Assoc. Editor: Brad Davis.

J. Med. Devices 7(4), 040925 (Dec 05, 2013) (2 pages) Paper No: MED-13-1246; doi: 10.1115/1.4025904 History: Received October 01, 2013; Revised October 29, 2013

The new transcatheter technique to implant synthetic aortic valves offers a treatment to patients previously considered untreatable. However, the majority of patients suffer from leakage alongside the implant. Using a statistical shape model of the anatomy, a correlation was discovered between leakage and the shape of the sinuses of Valsalva.

Copyright © 2013 by ASME
Topics: Modeling , Shapes , Valves , Leakage
Your Session has timed out. Please sign back in to continue.


Leon, M. B., Smith, C. R., Mack, M., Miller, D. C., Moses, J. W., Svensson, L. G., Tuzcu, E. M., Webb, J. G., Fontana, G. P., Makkar, R. R., Brown, D. L., Block, P. C., Guyton, R. A., Pichard, A. D., Bavaria, J. E., Herrmann, H. C., Douglas, P. S., Petersen, J. L., Akin, J. J., Anderson, W. N., Wang, D., Pocock, S., and PARTNER Trial Investigators, 2010, “Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery,” N. Engl. J. Med, 363(17), pp. 1597–1607. [CrossRef] [PubMed]
Huysmans, T., Sijbers, J., and Verdonk, B., 2010, “Automatic Construction of Correspondences for Tubular Surfaces,” IEEE Trans. Pattern Anal. Mach. Intell., 32(4), pp. 636–651. [CrossRef] [PubMed]


Grahic Jump Location
Fig. 1

The average shape and two first modes of variation of the statistical shape model of the aortic arch (N = 27)

Grahic Jump Location
Fig. 2

The parameter associated with component 11 of the aortic arch model is significantly lower (p = 0.0144) for patients with no or very little regurgitation




Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related Journal Articles
Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In