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Frontiers Abstracts

Hemodynamic Impact of Transcatheter Aortic Valve Deployment Configuration

[+] Author and Article Information
Wei Sun

Tissue Mechanics Laboratory,
University of Connecticut,
Storrs, CT 06269

Manuscript received September 27, 2013; final manuscript received October 14, 2013; published online December 5, 2013. Assoc. Editor: Jeffrey E. Bischoff.

J. Med. Devices 7(4), 040922 (Dec 05, 2013) (2 pages) Paper No: MED-13-1241; doi: 10.1115/1.4025938 History: Received September 27, 2013; Revised October 14, 2013

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Copyright © 2013 by ASME
Topics: Valves , Hemodynamics
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References

Grube, E., Schuler, G., Buellesfeld, L., Gerckens, U., Linke, A., Wenaweser, P., Sauren, B., Mohr, F.-W., Walther, T., Zickmann, B., Iversen, S., Felderhoff, T., Cartier, R., and Bonan, R., 2007, “Percutaneous Aortic Valve Replacement for Severe Aortic Stenosis in High-Risk Patients Using the Second- and Current Third-Generation Self-Expanding CoreValve Prosthesis: Device Success and 30-Day Clinical Outcome,” J. Am. Coll. Cardiol., 50(1), pp. 69–76. [CrossRef] [PubMed]
Webb, J. G., Pasupati, S., Humphries, K., Thompson, C., Altwegg, L., Moss, R., Sinhal, A., Carere, R. G., Munt, B., Ricci, D., Ye, J., Cheung, A., and Lichtenstein, S. V., 2007, “Percutaneous Transarterial Aortic Valve Replacement in Selected High-Risk Patients With Aortic Stenosis,” Circulation, 116(7), pp. 755–763. [CrossRef] [PubMed]
Zegdi, R., Lecuyer, L., Achouh, P., Didier, B., Lafont, A., Latrémouille, C., and Fabiani, J.-N., 2010, “Increased Radial Force Improves Stent Deployment in Tricuspid But Not in Bicuspid Stenotic Native Aortic Valves,” Ann. Thorac. Surg., 89(3), pp. 768–772. [CrossRef] [PubMed]
Zegdi, R., Ciobotaru, V., Noghin, M., Sleilaty, G., Lafont, A., Latrémouille, C., Deloche, A., and Fabiani, J.-N., 2008, “Is It Reasonable to Treat All Calcified Stenotic Aortic Valves With a Valved Stent? Results From a Human Anatomic Study in Adults,” J. Am. Coll. Cardiol., 51(5), pp. 579–584. [CrossRef] [PubMed]
Schultz, C. J., Weustink, A., Piazza, N., Otten, A., Mollet, N., Krestin, G., van Geuns, R. J., de Feyter, P., Serruys, P. W. J., and de Jaegere, P., 2009, “Geometry and Degree of Apposition of the CoreValve ReValving System With Multislice Computed Tomography After Implantation in Patients With Aortic Stenosis,” J. Am. Coll. Cardiol., 54(10), pp. 911–918. [CrossRef] [PubMed]
Li, K., and Sun, W., 2010, “Simulated Thin Pericardial Bioprosthetic Valve Leaflet Deformation Under Static Pressure-Only Loading Conditions: Implications for Percutaneous Valves,” Ann. Biomed. Eng., 38(8), pp. 2690–2701. [CrossRef] [PubMed]
Sun, W., Li, K., and Sirois, E., 2010, “Simulated Elliptical Bioprosthetic Valve Deformation: Implications for Asymmetric Transcatheter Valve Deployment,” J. Biomech., 43(16), pp. 3085–3090. [CrossRef] [PubMed]

Figures

Grahic Jump Location
Fig. 1

(a) Finite element simulation of valve opening, (b) leaflets placed on mounting ring, and (c) mounting ring placed in 38-mm tube

Grahic Jump Location
Fig. 2

Validation of simulation using experimental centerline pressure drop curve. Axial position of zero corresponds to test valve annulus.

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