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Frontiers Abstracts

Patient-Specific Simulations in Interventional Cardiology Practice: Early Results From a Clinical/Engineering Center

[+] Author and Article Information
Giovanni Biglino, Silvia Schievano

UCL Institute of Cardiovascular Science;
Great Ormond Street Hospital for Children,
Great Ormond Street,
London WC1N 3JH, UK

Graham Derrick

Great Ormond Street Hospital for Children,
Great Ormond Street,
London WC1N 3JH, UK

Philipp Bonhoeffer

Fondazione Toscana G. Monasterio,
Pisa 56124, Italy

Manuscript received September 27, 2013; final manuscript received November 8, 2013; published online December 5, 2013. Assoc. Editor: Jeffrey E. Bischoff.

J. Med. Devices 7(4), 040921 (Dec 05, 2013) (2 pages) Paper No: MED-13-1239; doi: 10.1115/1.4026044 History: Received September 27, 2013; Revised November 08, 2013

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References

Taylor, C. A., and Figueroa, C. A., 2009, “Patient-Specific Modeling of Cardiovascular Mechanics,” Ann. Rev. Biomed. Eng., 11, pp. 109–134. [CrossRef]
Schievano, S., Taylor, A. M., Capelli, C., Lurz, P., Nordmeyer, J., Migliavacca, F., and Bonhoeffer, P., 2010, “Patient Specific Finite Element Analysis Results in More Accurate Prediction of Stent Fractures: Application to Percutaneous Pulmonary Valve Implantation,” J. Biomechanics, 43(4), pp. 687–693. [CrossRef]
Keshavarz-Motamed, Z., Garcia, J., and Kadem, L., 2011, “Mathematical, Numerical and Experimental Study in the Human Aorta With Coexisting Models of Bicuspid Aortic Stenosis and Coarctation of the Aorta,” Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2011), Boston, MA, August 30-September 3, pp. 182–185. [CrossRef]
Viceconti, M., Clapworthy, G., and Jan, S. V. S., 2008, “The Virtual Physiological Human—A European Initiative for In Silico Human Modelling,” J. Physiol. Sci., 58(7), pp. 441–446. [CrossRef] [PubMed]
Schievano, S., Taylor, A. M., Capelli, C., Coats, L., Walker, F., Lurz, P., Nordmeyer, J., Wright, S., Khambadkone, S., Tsang, V., Carminati, M., and Bonhoeffer, P., 2010, “First-in-Man Implantation of a Novel Percutaneous Valve: A New Approach to Medical Device Development,” EuroIntervention, 5(6), pp. 745–750. [CrossRef] [PubMed]
Capelli, C., Biglino, G., Petrini, L., Migliavacca, F., Cosentino, D., Bonhoeffer, P., Taylor, A. M., and Schievano, S., 2012, “Finite Element Strategies to Satisfy Clinical and Engineering Requirements in the Field of Percutaneous Valves,” Annals Biomed. Engin., 40(12), 2663–2673. [CrossRef]

Figures

Grahic Jump Location
Fig. 1

Results of patient-specific simulations: (a)–(c) FE analyses of PPVI; (d) CFD visualization of stream flows following CoA stenting

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