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Technical Brief

Tissue Bond Strength as a Function of Applied Fusion Pressure1

[+] Author and Article Information
Nicholas Anderson, Eric Kramer, James Cezo, Virginia Ferguson, Mark E. Rentschler

Department of Mechanical Engineering,
University of Colorado at Boulder,
Boulder, CO 80309

Accepted and presented at the Design of Medical Devices Conference (DMD2014), Minneapolis, MN, April 7-10, 2014.DOI: 10.1115/1.4027046

Manuscript received February 21, 2014; final manuscript received March 3, 2014; published online July 21, 2014. Editor: Arthur G. Erdman.

J. Med. Devices 8(3), 030925 (Jul 21, 2014) (2 pages) Paper No: MED-14-1076; doi: 10.1115/1.4027046 History: Received February 21, 2014; Revised March 03, 2014

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References

Alimova, A., Chakraverty, R., Muthukattil, R., Elder, S., Katz, A., Sriramoju, V., Stanley, L., and Alfano, R. R., 2009, “In Vivo Molecular Evaluation of Guinea Pig Skin Incisions Healing After Surgical Suture and Laser Tissue Welding Using Raman Spectroscopy,” J. Photochem. Photobiol. B: Biol., 96(3), pp. 178–183. [CrossRef]
Hambley, R., Hebda, P. A., Abell, E., Cohen, B. A., and Jegasothy, B. V., 1988, “Wound Healing of Skin Incisions Produced by Ultrasonically Vibrating Knife, Scalpel, Electrosurgery, and Carbon Dioxide Laser,” J. Dermatol. Surg. Oncol., 14(11), pp. 1213–1217. [CrossRef] [PubMed]
Entezari, K., Hoffmann, P., Goris, M., Peltier, A., and Van Velthoven, R., 2007, “A Review of Currently Available Vessel Sealing Systems,” Minimally Invasive Ther. Allied Technol., 16(1), pp. 52–57. [CrossRef]
Bass, L. S., Moazami, N., Pocsidio, J., Oz, M. C., Logerfo, P., and Treat, M. R., 1992, “Changes in Type I Collagen Following Laser Welding,” Lasers Surg. Med., 12(5), pp. 500–505. [CrossRef] [PubMed]
Murray, L. W., Su, L., Kopchok, G. E., and White, R. A., 1989, “Crosslinking of Extracellular Matrix Proteins: A Preliminary Report on a Possible Mechanism of Argon Laser Welding,” Lasers Surg. Med., 9(5), pp. 490–496. [CrossRef] [PubMed]
Cezo, J. D., Kramer, E., Taylor, K., Ferguson, V., and Rentschler, M. E., 2013, “Temperature Measurement Methods During Direct Heat Arterial Tissue Fusion,” IEEE Trans. Biomed. Eng., 60(9), pp. 2552–2558. [CrossRef] [PubMed]
Cezo, J. D., Passernig, A., Ferguson, V., Taylor, K., and Rentschler, M. E., 2013, “Evaluating Temperature and Duration in Arterial Tissue Fusion to Maximize Bond Strength,” J. Mech. Behav. Biomed. Mater., 30, pp. 41–49. [CrossRef]

Figures

Grahic Jump Location
Fig. 1

Custom fusion device allowing for precise variation of applied load during fusion. Tubular artery sections are placed between the device jaws with the artery axis perpendicular to the long axis of the jaws. The MTS is then used to apply a specified load while the heaters are simultaneously activated.

Grahic Jump Location
Fig. 2

Box and whisker plots of burst pressure normalized for vessel thickness versus load applied during fusion. The horizontal axis is not linear. Median values are displayed in each box, and crosses indicate outliers, defined as points outside of two times the standard deviation.

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