Technical Brief

In Vivo Monitoring of HIFU Induced Temperature Rise in Porcine Liver Using Magnetic Resonance Thermometry1

[+] Author and Article Information
Seyed Ahmad Reza Dibaji, Rupak K. Banerjee

Department of Mechanical and Materials Engineering,
College of Engineering and Applied Science,
University of Cincinnati,
Cincinnati, OH 45221

Janaka Wansapura

Imaging Research Center,
Cincinnati Children's Hospital Medical Center,
Cincinnati, OH 45221

Matthew R. Myers

Division of Solid and Fluid Mechanics,
Center for Devices and Radiological Health,
U.S. Food and Drug Administration,
Silver Spring, MD 20993

Accepted and presented at the Design of Medical Devices Conference (DMD2014), Minneapolis, MN, April 7–10, 2014.

Manuscript received February 21, 2014; final manuscript received March 3, 2014; published online July 21, 2014. Editor: Arthur G. Erdman.

J. Med. Devices 8(3), 030937 (Jul 21, 2014) (2 pages) Paper No: MED-14-1088; doi: 10.1115/1.4027082 History: Received February 21, 2014; Revised March 03, 2014

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Morris, H., Rivens, I., Shaw, A., and Haar, G. T., 2008, “Investigation of the Viscous Heating Artifact Arising From the Use of Thermocouples in a Focused Ultrasound Field,” Phys. Med. Biol., 53(17), pp. 4759–4776. [CrossRef] [PubMed]
Dasgupta, S., Hariharan, P., Banerjee, R. K., and Myers, M. R., 2011, “Beam Localization in HIFU Temperature Measurements Using Thermocouples, With Application to Cooling by Large Blood Vessels,” Ultrasonics, 51(2), pp. 171–180. [CrossRef] [PubMed]
Dasgupta, S., Wansapura, J., Hariharan, P., Pratt, R., Witte, D., Myers, M. R., and Banerjee, R. K., 2010, “HIFU Lesion Volume as a Function of Sonication Time, as Determined by MRI, Histology, and Computations,” ASME J. Biomech. Eng., 132(8), p. 081005. [CrossRef]
Quesson, B., Laurent, C., Maclair, G., de Senneville, B. D., Mougenot, C., Ries, M., Carteret, T., Rullier, A., and Moonen, C. T., 2011, “Real-Time Volumetric MRI Thermometry of Focused Ultrasound Ablation In Vivo: A Feasibility Study in Pig Liver and Kidney,” NMR Biomed., 24(2), pp. 145–153. [CrossRef] [PubMed]
Dasgupta, S., Das, P., Wansapura, J., Hariharan, P., Pratt, R., Witte, D., Myers, M. R., and Banerjee, R. K., 2011, “Reduction of Noise From MR Thermometry Measurements During HIFU Characterization Procedures,” ASME J. Nanotechnol. Eng. Med., 2(2), p. 024501. [CrossRef]
Rieke, V., Vigen, K. K., Sommer, G., Daniel, B. L., Pauly, J. M., and Butts, K., 2004, “Referenceless PRF Shift Thermometry,” Magn. Reson. Med., 51(6), pp. 1223–1231. [CrossRef] [PubMed]


Grahic Jump Location
Fig. 1

Schematic of HIFU experimental setup

Grahic Jump Location
Fig. 3

HIFU induced temperature rise in porcine liver with sonication period of 30 s using acoustic powers of (a) 10 W, (b) 30 W, and (c) 40 W

Grahic Jump Location
Fig. 2

Highest temperature map for the acoustic powers of (a) 30 W and (b) 40 W



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