Technical Brief

Intracoronary Injection of Medication From Multilumen Injection Catheters1

[+] Author and Article Information
Brian Plourde, Dillon Schwalbach, John Abraham

School of Engineering,
University of St. Thomas,
2115 Summit Ave.,
St. Paul, MN 55105

Rob Kohler

Translational Research Institute,
3420 S. Mercy Road, Suite 312,
Gilbert, AZ 85297

Accepted and presented at the Design of Medical Devices Conference (DMD2014), Minneapolis, MN, April 7–10, 2014.

Manuscript received February 21, 2014; final manuscript received February 28, 2014; published online April 28, 2014. Editor: Arthur G. Erdman.

J. Med. Devices 8(2), 020901 (Apr 28, 2014) (2 pages) Paper No: MED-14-1030; doi: 10.1115/1.4027001 History: Received February 21, 2014; Revised February 28, 2014

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Copyright © 2014 by ASME
Topics: Catheters , Drugs
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Schwalbach, D. B., Plourde, B. D., Abraham, J. P., and Kohler, R. E., 2014, “Drug Dispersion for Single- and Multi-Lumen Catheters,” J. Biomed. Sci. Eng., 7, pp. 7–14. [CrossRef]
Abraham, J. P., Sparrow, E. M., Gorman, J. M., Stark, J. R., and Kohler, R. E., 2013, “A Mass Transfer Model of Temporal Drug Deposition in Artery Walls,” Int. J. Heat Mass Transfer, 58(1–2), pp. 632–638. [CrossRef]
Abraham, J. P., Stark, J. R., Gorman, J. M., Sparrow, E. M., and Kohler, R. E., 2013, “A Model of Drug Deposition Within Artery Walls,” ASME J. Med. Devices, 7(2), p. 020901. [CrossRef]
Stark, J. R., Gorman, J. M., Sparrow, E. M., Abraham, J. P., and Kohler, R. E., 2013, “Controlling the Rate of Penetration of a Therapeutic Drug Into the Wall of an Artery by Means of a Pressurized Balloon,” J. Biomed. Sci. Eng., 61, pp. 527–532. [CrossRef]


Grahic Jump Location
Fig. 1

Multilumen catheter with callouts showing important geometric features (reproduced from Ref. [1])

Grahic Jump Location
Fig. 2

Cross sectional view of catheter positioned in artery

Grahic Jump Location
Fig. 3

Impact of medication spreading rate to diffusivity (from Ref. [1])

Grahic Jump Location
Fig. 4

Areas occupied by medication concentrations exceeding 1% by volume



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