Technical Brief

Cardiovascular Impacts of High Frequency Chest Compression1

[+] Author and Article Information
George O'Clock, Jongwon Lee, Yong Wan Lee

Department of Pediatrics,
Defense of the Lung Project,
University of Minnesota Medical School,
Minneapolis, MN 55455

Accepted and presented at the Design of Medical Devices Conference (DMD2014), Minneapolis, MN, April 7–10, 2014.

Manuscript received February 21, 2014; final manuscript received February 28, 2014; published online April 28, 2014. Editor: Arthur G. Erdman.

J. Med. Devices 8(2), 020907 (Apr 28, 2014) (2 pages) Paper No: MED-14-1036; doi: 10.1115/1.4027007 History: Received February 21, 2014; Revised February 28, 2014

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Lee, Y. W., Lee, J., and Warwick, W. J., 2008, “Waveforms of High-Frequency Chest Compression Systems Change With Jacket, Body,” Biomed. Instrum. Technol., 42(5), pp. 407–411. [CrossRef]
O'Clock, G. D., Lee, Y. W., Lee, J., and Warwick, W. J., 2012, “High-Frequency and Low-Frequency Chest Compression Effects on Lung Water Secretion, Mucus Transport, Heart Rate and Blood Pressure Using a Trapezoidal Source Pressure Waveform,” IEEE Trans. Biomed. Eng., 59(1), pp. 106–114. [CrossRef]
Allan, J. S., Garrity, J. M., and Donahue, D. M., 2009, “High-Frequency Chest Compression During the 48 Hours Following Thoracic Surgery,” Respir. Care, 54(3) pp. 340–343.


Grahic Jump Location
Fig. 1

Predicted FEV1 plot (forced expiratory volume in one second) showing two CF patients with FEV1 levels above 50% just before their life ended, and two who survived with much lower FEV1 levels, living almost as long, or longer, compared with their higher FEV1 counterparts. This IRB approved data were presented in the 22nd and 23rd Annual North American Cystic Fibrosis Conference in 2008 and 2009, and the 32nd European Cystic Fibrosis Conference in Brest, France in 2009.

Grahic Jump Location
Fig. 2

Graph of heart rate versus time for an HFCC frequency of 1.5 Hz at 50% maximum vest pressure. A heart rate decrease occurs 55 s after treatment begins.




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