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Technical Brief

Multijoint Rigidity-Testing Device for Titrating Medication and Deep Brain Stimulation Therapies1

[+] Author and Article Information
Kevin J. Mohsenian, Allison T. Connolly, Matthew D. Johnson

Department of Biomedical Engineering,
University of Minnesota,
Minneapolis, MN 55455

Accepted and presented at the Design of Medical Devices Conference (DMD2014), Minneapolis, MN, April 7–10, 2014.

2Corresponding author.

Manuscript received February 21, 2014; final manuscript received February 28, 2014; published online April 28, 2014. Editor: Arthur G. Erdman.

J. Med. Devices 8(2), 020920 (Apr 28, 2014) (2 pages) Paper No: MED-14-1050; doi: 10.1115/1.4027021 History: Received February 21, 2014; Revised February 28, 2014

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References

Patrick, S. K., Denington, A. A., Gauthier, M. J., Gillard, D. M., and Prochazka, A., 2001, “Quantification of the UPDRS Rigidity Scale,” IEEE Trans. Neural Syst. Rehabil. Eng., 9(1), pp. 31–41. [CrossRef]
Webster, D. D., 1959, “A Method of Measuring the Dynamic Characteristics of Muscle Rigidity Strength and Tremor in the Upper Extremity,” IRE Trans. Med. Electron., 6(3), pp. 159–164. [CrossRef]
Watts, R. L., Wiegner, A. W., and Young, R. R., 1986, “Elastic Properties of Muscles Measured at the Elbow in Man: II. Patients With Parkinsonian Rigidity,” J. Neurol. Neurosurg. Psychiatry, 49(10), pp. 1177–1181. [CrossRef]
Mera, T. O., Johnson, M. D., Rothe, D., Zhang, J., Xu, W., Ghosh, D., Vitek, J., and Alberts, J. L., 2009, “Objective Quantification of Armrigidity in MPTP-Treated Primates,” J. Neurosci. Methods, 177(1), pp. 20–29. [CrossRef]
Prochazka, A., Bennett, D. J., Stephens, M. J., Patrick, S. K., Sears-Duru, R., Roberts, T., and Jhamandas, J. H., 1997, “Measurement of Rigidity in Parkinson's Disease,” Mov. Disord., 12(1), pp. 24–32. [CrossRef]

Figures

Grahic Jump Location
Fig. 2

Elbow (top) and knee (bottom) force–angle curves for (a) and (e) MPTP; (b) and (f) MPTP + DBS; (c) and (g) MPTP + Sinemet (mean ± standard error); and (d) and (h) Flexion–extension curve areas over ten articulations for each force–angle plot. **p < 0.01.

Grahic Jump Location
Fig. 1

(a) Position of the shoulder, elbow, and wrist during elbow joint articulation. (b) Elbow angle during articulations. (c) Schematic drawing of data acquisition set-up. (d) Differential force measurements during elbow articulations. (e) Force–angle curves of elbow flexion/extension.

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