Technical Brief

Paradigm Shift Allows for Readily Available Therapeutic Hypothermia Treatment of the Head Region1

[+] Author and Article Information
Michael Zumbrunnen

InControl Biomedical LLC,
Rochester, MN 55902

Accepted and presented at the Design of Medical Devices Conference (DMD2014), Minneapolis, MN, April 7–10, 2014.DOI: 10.1115/1.4027020

Manuscript received February 21, 2014; final manuscript received February 28, 2014; published online April 28, 2014. Editor: Arthur G. Erdman.

J. Med. Devices 8(2), 020921 (Apr 28, 2014) (2 pages) Paper No: MED-14-1049; doi: 10.1115/1.4027020 History: Received February 21, 2014; Revised February 28, 2014

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Froehler, M. T., and Ovbiagele, B., 2010, “Therapeutic Hypothermia for Acute Ischemic Stroke,” Expert Rev. Cardiovasc. Ther., 8(4), pp. 593–603. [CrossRef]
Yenan, M. A., and Han, H. S., 2012, “Neuroprotective Mechanisms of Hypothermia in Brain Ischaemia,” Nat. Rev. Neurosci., 13(4), pp. 267–268. [CrossRef]
Ohley, W. J., 2010, “Evidence for Benefits of Rapid Induction of Hypothermia,” University of Rhode Island, Kingston, RI, Technical Report No. 20100001.
Jansen, F. E., Van Leeuwen, G. M., and Van Steenhoven, A. A., 2005, “Modelling of Temperature and Perfusion During Scalp Cooling,” Phys. Med. Biol., 50(17), pp. 4065–4073. [CrossRef]
Breed, W. P. M., van den Hurk, C. J. G., and Peerbooms, M., 2011, “Impact and Prevention of Chemotherapy-Induced Hair Loss; Scalp Cooling Potentials and Limitations,” Expert Rev. Dermatol., 6(1), pp. 109–125. [CrossRef]


Grahic Jump Location
Fig. 1

View of hair with gel applied

Grahic Jump Location
Fig. 2

Thermocouple probes radially inserted in cap

Grahic Jump Location
Fig. 3

Temperature profile for khair (dry) = 0.026 W/m K and for khair (gelled) = 0.26 W/m K

Grahic Jump Location
Fig. 4

Measured skin temperature (°C)



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