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Special Section Technical Briefs

Acute Shrinkage of the Pulmonary Vein Ensuing From Radiofrequency and Cryoablations1

[+] Author and Article Information
Stephen G. Quallich, Paul A. Iaizzo

Departments of Biomedical Engineering and Surgery,
University of Minnesota,
Minneapolis, MN 55455

Accepted and presented at The Design of Medical Devices Conference (DMD2015), April 13-16, 2015, Minneapolis, MN, USA.

Manuscript received March 3, 2015; final manuscript received March 16, 2015; published online April 24, 2015. Editor: Arthur Erdman.

J. Med. Devices 9(2), 020904 (Jun 01, 2015) (2 pages) Paper No: MED-15-1039; doi: 10.1115/1.4030121 History: Received March 03, 2015; Revised March 16, 2015; Online April 24, 2015

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Figures

Grahic Jump Location
Fig. 4

Performing RF ablations produced a reduction in observed circumferential stresses for only the human ostia (n = 3) when compared to the swine ostia (n = 8). No differences were observed between the distal human (n = 3) and distal swine (n = 9) groups.

Grahic Jump Location
Fig. 3

Normalized circumferential stresses following distal RF ablation (n = 9) were significantly different compared to the nontreatment controls, while cryoablation (n = 8) was only significantly different during thaw (*p < 0.05 for RF ablation, **p < 0.05 for cryoablation)

Grahic Jump Location
Fig. 2

Graphical representation of strain imposed on the PV sample throughout the experiment. The ablation was started at the 60 s time point.

Grahic Jump Location
Fig. 1

The PV specimens were mounted on a biaxial testing machine using sutures in alignment with the axial and circumferential directions of a given vessel

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