Special Section Technical Briefs

Ocular Blood Flow Response to Applied Force: In Vivo Tests Toward Noninvasive Intracranial Pressure Monitoring1

[+] Author and Article Information
Jeff A. Hawks, Chase Pfeifer, Mason Spilinek

Department of Mechanical and Materials Engineering,
University of Nebraska–Lincoln,
Lincoln, NE 68588

Max Twedt, Ellie Ahlquist, Madison Burger

Department of Biological Systems Engineering,
University of Nebraska–Lincoln,
Lincoln, NE 68588

William Thorell

Department of Neurosurgery,
University of Nebraska Medical Center,
Omaha, NE 68198

James Gigantelli

Department of Ophthalmology,
University of Nebraska Medical Center,
Omaha, NE 68198

Greg Bashford

Department of Biological Systems Engineering,
University of Nebraska–Lincoln,
Omaha, NE 68198

Accepted and presented at The Design of Medical Devices Conference (DMD2015), April 13-16, 2015, Minneapolis, MN, USA.

Manuscript received March 3, 2015; final manuscript received March 16, 2015; published online April 24, 2015. Editor: Arthur Erdman.

J. Med. Devices 9(2), 020911 (Jun 01, 2015) (3 pages) Paper No: MED-15-1046; doi: 10.1115/1.4030119 History: Received March 03, 2015; Revised March 16, 2015; Online April 24, 2015

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Copyright © 2015 by ASME
Topics: Pressure , Blood flow
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Grahic Jump Location
Fig. 1

Blood flow velocity via transcranial Doppler (left) and transducer instrumented with axial load cell (right)

Grahic Jump Location
Fig. 2

Inserting the lumbar catheter (left) and position of the ICP monitor in the right frontal lobe (right)

Grahic Jump Location
Fig. 3

Sample in vivo test results at 28 mm Hg

Grahic Jump Location
Fig. 4

RI and PI before force is applied to the cornea

Grahic Jump Location
Fig. 5

RI percent change during applied versus ICP level




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