Special Section Technical Briefs

The Treatment of Acute Respiratory Distress Syndrome in Rats With a Peritoneal Dosing System1

[+] Author and Article Information
Nathan Legband, Benjamin Terry

Department of Mechanical and Material Engineering,
University of Nebraska–Lincoln,
Lincoln, NE 68588

Keely Buesing

Department of Surgery,
University of Nebraska Medical Center,
Omaha, NE 68198

Mark Borden

Department of Mechanical Engineering,
University of Colorado–Boulder,
Boulder, CO 80302

Accepted and presented at The Design of Medical Devices Conference (DMD2015), April 13-16, 2015, Minneapolis, MN, USA.

Manuscript received March 3, 2015; final manuscript received March 16, 2015; published online April 24, 2015. Editor: Arthur Erdman.

J. Med. Devices 9(2), 020929 (Jun 01, 2015) (2 pages) Paper No: MED-15-1122; doi: 10.1115/1.4030140 History: Received March 03, 2015; Revised March 16, 2015; Online April 24, 2015

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Fitzgerald, M., Millar, J., Blackwood, B., Davies, A., Brett, S. J., McAuley, D. F., and McNamee, J. J., 2014, “Extracorporeal Carbon Dioxide Removal for Patients With Acute Respiratory Failure Secondary to the Acute Respiratory Distress Syndrome: A Systematic Review,” Crit. Care, 18(3), pp. 1–11. [CrossRef]
Feshitan, J. A., Legband, N. D., Borden, M. A., and Terry, B. S., 2014, “Systemic Oxygen Delivery by Peritoneal Perfusion of Oxygen Microbubbles,” Biomaterials, 35(9), pp. 2600–2606. [CrossRef] [PubMed]
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Erdem, M. K., Yurdakan, G., and Yilmaz-Sipahi, E., 2014, “The Effects of Ketamine, Midazolam and Ketamine/Xylazine on Acute Lung Injury Induced by A-Naphthylthiourea in Rats,” Adv. Clin. Exp. Med., 23(3), pp. 343–351. [CrossRef] [PubMed]


Grahic Jump Location
Fig. 1

Representative chest radiographs of rat given LPS

Grahic Jump Location
Fig. 2

Average peripheral oxygen saturation (SpO2) levels of each group measured from pulse oximetry during observation period

Grahic Jump Location
Fig. 3

Schematic of PDS for rat



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