Special Section Technical Briefs

Inferring Gene Regulatory Networks by Context Dependent and Independent Effects1

[+] Author and Article Information
Wuming Gong, Koyano-Nakagawa Naoko, Daniel J. Garry

Lillehei Heart Institute,
University of Minnesota,
Minneapolis, MN 55455

Accepted and presented at The Design of Medical Devices Conference (DMD2015), April 13–16, 2015, Minneapolis, MN, USA.

Manuscript received March 3, 2015; final manuscript received March 17, 2015; published online July 16, 2015. Editor: Arthur Erdman.

J. Med. Devices 9(3), 030947 (Sep 01, 2015) (3 pages) Paper No: MED-15-1103; doi: 10.1115/1.4030577 History: Received March 03, 2015; Revised March 17, 2015; Online July 16, 2015

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Grahic Jump Location
Fig. 1

Modeling GRN of early ESC differentiation by NICE using temporal microarray dataset perturbing 50 TFs. ((a)–(c)) observed expression levels in Dox and Dox+ samples at 48 hrs for Pou5f1, Sox2, and T. ((d)–(f)) observed expression levels in Dox and predicted expression levels at 48 hrs for Pou5f1, Sox2, and T (cc: correlation coefficient).




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