Special Section Technical Briefs

Peritoneal Membrane Oxygenation Therapy for Rats With Acute Respiratory Distress Syndrome1

[+] Author and Article Information
Nathan Legband, Liana Hatoum, Benjamin Terry

Department of Mechanical and Material Engineering,
University of Nebraska-Lincoln,
Lincoln, NE 68588

Alec Thomas, Mark Borden

Department of Mechanical Engineering,
University of Colorado-Boulder,
Boulder, CO 80309

Craig Kreikemeier-Bower

Institutional Animal Care Program,
University of Nebraska-Lincoln,
Lincoln, NE 68583

Douglas Hostetler

Department of Veterinarian Medicine
and Biomedical Sciences,
University of Nebraska-Lincoln,
Lincoln, NE 68583

Keely Buesing

Department of Surgery,
University of Nebraska Medical Center,
Omaha, NE 68198

DOI: 10.1115/1.4033201Manuscript received March 1, 2016; final manuscript received March 17, 2016; published online May 12, 2016. Editor: William Durfee.

J. Med. Devices 10(2), 020905 (May 12, 2016) (2 pages) Paper No: MED-16-1150; doi: 10.1115/1.4033201 History: Received March 01, 2016; Revised March 17, 2016

First Page Preview

View Large
First page PDF preview
Copyright © 2016 by ASME
Your Session has timed out. Please sign back in to continue.


Choi, W.-I. , Shehu, E. , Lim, S. Y. , Koh, S. O. , Jeon, K. , Na, S. , Lim, C.-M. , Lee, Y.-J. , Kim, S. C. , Kim, I. H. , Kim, J. H. , Kim, J. Y. , Lim, J. , Rhee, C. K. , Park, S. , Kim, H. C. , Lee, J. H. , Lee, J. H. , Park, J. , Koh, Y. , and Suh, G. Y. , 2014, “ Markers of Poor Outcome in Patients With Acute Hypoxemic Respiratory Failure,” J. Crit. Care, 29(5), pp. 797–802. [CrossRef] [PubMed]
Feshitan, J. A. , Legband, N. D. , Borden, M. A. , and Terry, B. S. , 2014, “ Systemic Oxygen Delivery by Peritoneal Perfusion of Oxygen Microbubbles,” Biomaterials, 35(9), pp. 2600–2606. [CrossRef] [PubMed]
Van Helden, H. P. M. , Kuijpers, W. C. , Steenvoorden, D. , Go, C. , Bruijnzeel, P. L. B. , van Eijk, M. , and Haagsman, H. P. , 1997, “ Intratracheal Aerosolization of Endotoxin (LPS) in the Rat: A Comprehensive Animal Model to Study Adult (Acute) Respiratory Distress Syndrome,” Exp. Lung Res., 23(4), pp. 297–316. [CrossRef] [PubMed]


Grahic Jump Location
Fig. 1

Design of PDS for continuous infusion to a rat

Grahic Jump Location
Fig. 2

Peripheral oxygen saturation for rats with ARDS (average with standard error bars) and preliminary trials treated with OMBs (MR)

Grahic Jump Location
Fig. 3

Chest radiographs of MRP versus ARDS rats



Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related Journal Articles
Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In