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Special Section Technical Briefs

Identifying Biomarkers for Intracranial Pressure Changes in the Development of a Noninvasive Monitoring Device1

[+] Author and Article Information
Jeff A. Hawks

Department of Mechanical and Materials Engineering,
University of Nebraska-Lincoln,
Lincoln, NB 68588

Greg Bashford

Department of Biological Systems Engineering,
University of Nebraska-Lincoln,
Lincoln, NB 68588

Sachin Kedar

Department of Neurological Science,
University of Nebraska Medical Center,
Omaha, NB 68198

William Thorell

Department of Neurosurgery,
University of Nebraska Medical Center,
Omaha, NB 68198

Deepta Ghate

Department of Ophthalmology and Visual Sciences,
University of Nebraska Medical Center,
Omaha, NB 68198

DOI: 10.1115/1.4033202Manuscript received March 1, 2016; final manuscript received March 17, 2016; published online May 12, 2016. Editor: William Durfee.

J. Med. Devices 10(2), 020907 (May 12, 2016) (2 pages) Paper No: MED-16-1151; doi: 10.1115/1.4033202 History: Received March 01, 2016; Revised March 17, 2016

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Copyright © 2016 by ASME
Topics: Pressure
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References

Lee, S. C. M. , and Lueck, C. J. , 2014, “ Cerebrospinal Fluid Pressure in Adults,” J. Neuro-Ophthalmol., 34(3), pp. 278–283. [CrossRef]
Yang, Y. , Yu, M. , Zhu, J. , Chen, X. , and Liu, X. , 2010, “ Role of Cerebrospinal Fluid in Glaucoma: Pressure and Beyond,” Med. Hypotheses, 74(1), pp. 31–34. [CrossRef] [PubMed]
Brain Trauma Foundation, 2007, “ Guidelines for the Management of Severe Traumatic Brain Injury,” J. Neurotrauma, 24(Suppl. 1), p. S45. [PubMed]
Kristiansson, H. , Nissborg, E. , Bartek, J., Jr. , Andresen, M. , Reinstrup, P. , and Romner, B. , 2013, “ Measuring Elevated Intracranial Pressure Through Noninvasive Methods: A Review of the Literature,” J. Neurosurg. Anesthesiol., 25(4), pp. 372–385. [CrossRef] [PubMed]
Bruce, B. B. , 2014, “ Noninvasive Assessment of Cerebrospinal Fluid Pressure,” J. Neuro-Ophthalmol., 34(3), pp. 288–294. [CrossRef]
Fogarty, J. A. , Otto, C. , Kerstman, E. , Oubre, C. , and Wu, J. , 2011, “ The Visual Impairment Intracranial Pressure Summit Report,” NASA Johnson Space Center, Houston, TX, Report No. NASA/TP-2011-216160.

Figures

Grahic Jump Location
Fig. 1

ONH image using SD-OCT

Grahic Jump Location
Fig. 2

OCT image of the ONH at ICP of 4 mm Hg

Grahic Jump Location
Fig. 3

OCT images of the ONH at ICP of 12 mm Hg

Grahic Jump Location
Fig. 4

OCT image of the ONH at 23 mm Hg

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