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Special Section Technical Briefs

A D-Shaped Bileaflet Bioprosthesis Which Replicates Physiological Left Ventricular Flow Patterns1

[+] Author and Article Information
Guo-Dong Sean Tan, Hwa Liang Leo

Department of Biomedical Engineering,
National University of Singapore,
117583, Singapore

DOI: 10.1115/1.4033119Manuscript received March 1, 2016; final manuscript received March 16, 2016; published online May 12, 2016. Assoc. Editor: William Durfee.

J. Med. Devices 10(2), 020910 (May 12, 2016) (3 pages) Paper No: MED-16-1059; doi: 10.1115/1.4033119 History: Received March 01, 2016; Revised March 16, 2016

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References

Bach, D. S. , 1997, “Stress Echocardiography for Evaluation of Hemodynamics: Valvular Heart Disease, Prosthetic Valve Function, and Pulmonary Hypertension,” Prog. Cardiovasc. Dis., 39(6), pp. 543–554. [CrossRef] [PubMed]
Valfre, C. , Lus, P. , Giuseppe, M. , Salvador, L. , Bottio, T. , Cesari, F. , Rizzoli, G. , and Gerosa, G. , 2010, “The Fate of Hancock II Porcine Valve Recipients 25 Years After Implant,” Eur. J. Cardiothorac. Surg., 38(2), pp. 141–145. [CrossRef] [PubMed]
Magilligan, D. J., Jr. , Lewis, J. W., Jr. , Tilley, B. , and Peterson, E. , 1985, “The Porcine Bioprosthetic Valve: Twelve Tears Later,” J. Thorac. Cardiovasc. Surg., 89(4), pp. 499–507. [PubMed]
Faludi, R. , Szulik, M. , D'Hooge, J. , Herijgers, P. , Rademakers, F. , Pedrizzetti, G. , and Voigt, J. U. , 2010, “Left Ventricular Flow Patterns in Healthy Subjects and Patients With Prosthetic Mitral Valves: An In Vivo Study Using Echocardiographic Particle Image Velocimetry,” J. Thorac. Cardiovasc. Surg., 139(6), pp. 1501–1510. [CrossRef] [PubMed]
Pedrizzetti, G. , Domenichini, F. , and Tonti, G. , 2010, “On the Left Ventricular Vortex Reversal After Mitral Valve Replacement,” Ann. Biomed. Eng., 38(3), pp. 769–773. [CrossRef] [PubMed]
Pierrakos, O. , and Vlachos, P. P. , 2006, “The Effect of Vortex Formation on Left Ventricular Filling and Mitral Valve Efficiency,” ASME J. Biomech. Eng., 128(4), pp. 527–539. [CrossRef]
Jamieson, W. R. E. , Lewis, C. T. P. , Sakwa, M. P. , Cooley, D. A. , Kshettry, V. R. , Jones, K. W. , David, T. E. , Sullivan, J. A. , Fradet, G. J. , and Bach, D. S. , 2011, “St Jude Medical Epic Porcine Bioprosthesis: Results of the Regulatory Evaluation,” J. Thorac. Cardiovasc. Surg., 141(6), pp. 1449–1454. [CrossRef] [PubMed]
Shen, M. , Carpentier, S. M. , Cambillau, M. , Chen, L. , Martinet, B. , and Carpentier, A. , 2001, “Protein Adsorption in Glutaraldehyde-Preserved Bovine Pericardium and Porcine Valve Tissues,” Ann. Thorac. Surg., 71(5), pp. S408–S409. [CrossRef] [PubMed]

Figures

Grahic Jump Location
Fig. 4

Flow patterns of both epic and GD valves

Grahic Jump Location
Fig. 3

Pressure and flow waveform of epic valve ((a) and (c)) and GD valve ((b) and (d))

Grahic Jump Location
Fig. 2

Experimental setup

Grahic Jump Location
Fig. 1

Engineering dimensions of GD valve

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