Background: As the connection at the proximal tip plays an important role for sensing guidewires, we compared various sensing guidewires with regard to their proximal connectors. The strengths and weaknesses of each are discussed and recommendations for future development are provided.
Method: A literature search was carried out on the USPTO database, Espacenet and Web of Science and was limited to the English language for the time period from the 1960s to the 2010s. The results were categorized on the basis of the connector design.
Results: A comprehensive overview and classification of proximal connectors for sensing guidewires used for cardiovascular interventions is presented. The classification is based on the type of connector (fixed or removable) and the type of connection (physical, wireless, or a combination).
Conclusion: Considering the complexity of the currently prototyped and tested connectors, future connector development will necessitate an easy and cost effective manufacturing process that can ensure safe and robust connections.