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Technical Brief

Using Simulation to Help Specify Design Parameters for Vacuum-Assisted Needle Biopsy Systems

[+] Author and Article Information
Xuelian Gu

School of Medical Instrument
and Food Engineering,
Shanghai Institute for Minimally Invasive Therapy,
University of Shanghai for Science and Technology,
516 Jungong Road,
Shanghai 200093, China
e-mail: guxuelian@usst.edu.cn

Fangqiu Hu, Licheng Lu

School of Medical Instrument
and Food Engineering,
Shanghai Institute for Minimally Invasive Therapy,
University of Shanghai for Science and Technology,
516 Jungong Road,
Shanghai 200093, China

Chi-Lun Lin

Department of Mechanical Engineering,
National Cheng Kung University,
No. 1 University Road, East District,
Tainan City 701, Taiwan

Arthur Erdman

Department of Mechanical Engineering,
University of Minnesota,
111 Church St SE #1100,
Minneapolis, MN 55455
e-mail: agerdman@umn.edu

1Corresponding authors.

2F. Hu contributed equally to this work.

Manuscript received February 26, 2018; final manuscript received September 12, 2018; published online November 19, 2018. Assoc. Editor: Rafael V. Davalos.

J. Med. Devices 13(1), 014502 (Nov 19, 2018) (7 pages) Paper No: MED-18-1042; doi: 10.1115/1.4041487 History: Received February 26, 2018; Revised September 12, 2018

Needle biopsy is a routine medical procedure for examining tissue or biofluids for the presence of disease using standard methods of pathology. The finite element analysis (FEA) methodology can provide guidance for optimizing the geometric parameters. The needle biopsy is simulated and analyzed while varying the needle angle, the aperture size and the slice-push ratio k. The results indicate that tissue reaction force in the axial direction of needle gradually decreases, and the stress and strain are more concentrated at the tip of needle with the increases of tip angle; the tissue reaction force decreases, and the torque increases while the slice-push ratio increases; and higher slice–push ratio can increase the peak stress concentration on the cutting edge and deformation of tissue; in the process of core needle cutting, increasing slice–push ratio can reduce the tissue reaction force significantly. While the aperture on distal wall of outer cannula becomes wider, the tissue reaction force increases significantly, and the cutting process will be more unstable. The results have the potential to provide important insight for improving the needle biopsy design process.

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References

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Figures

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Fig. 1

The coaxial needle system

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Fig. 2

Geometry model of needle biopsy

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Fig. 3

von Mises stress contour of the deformed soft tissue: (a) tip angle 15 deg and (b) tip angle 45 deg

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Fig. 4

Maximum principal strain contours of the deformed soft tissue: (a) tip angle 15 deg and (b) tip angle 45 deg

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Fig. 5

Force–time curve of needle insertion

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Fig. 6

Force–displacement curve of needle insertion

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Fig. 7

von Mises stress contour of the deformed soft tissue

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Fig. 8

Force–displacement curve of cutting under different tissue width, solid line: k = 0, dotted line: k = 1

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Fig. 9

Force–displacement curve of tissue cutting under different slice–push ratio k: (a) width = 1.8 mm, (b) width = 2.5 mm

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