Utilization of numerical simulations has been increased rapidly to test many innovative concepts in the field of advanced fuel technologies. Implementation of chemical compound's interaction is viable option by numerical tools. Hence in this current study, the numerical simulation has been performed to evaluate the effect of spray velocities on the mass fraction of various compounds. The conceptual numerical domain has been constructed with mixture of two inlets such as air and CH4 using ansys-cfd. In addition to the CH4, the nanoparticles were injected in the same inlet using the volume of fluid method. The fuel was injected at different velocities varied from 100 m/s to 175 m/s, under the intervals of 25 m/s. Here two sections of the domains are created, one for the oxidizers and another for the CH4 with nanoparticles. Throughout the entire trial runs, the nanoparticle concentration has been maintained constant. A series of the pictorial contours have been captured to understand the influence of the fuel impinging characteristics and reaction rates in the combustion chamber. The results revealed that CH4 injection enhances the vortices formation inside the combustion chamber. Furthermore, turbulence intensity inside the chamber is high which delays the reaction time and leads to the higher combustion indeed.